Research

Clinical Research Studies

See below for a list of clinical research studies open to patient recruitment in the Network;

 

Bradford Teaching Hospitals NHS Foundation Trust

  • Diligen- Pharmocogenetics of drug induced liver injury
  • HCV Research UK- Host and Viral factors associated with outcomes of infection with hepatitis C virus
  • PBC Genetics Study- Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis 
  • STOPAH- Steroids or pentoxifylline for alcoholic hepatitis
  • UK-PSC- A UK collaborative study to determine the genetic basis of Primary Sclerosing Cholangitis

 Leeds Teaching Hospitals NHS Trust

  • Diligen- Pharmocogenetics of drug induced liver injury. 
  • HCV Research UK- Host and Viral factors associated with outcomes of infection with hepatitis C virus 
  • HepRiACT (Academic trial) Evaluate the biological effects of administering rimantadine in patients with hepatitis C alongside standard combination therapy 
  • LEAN- A 48-week phase II, randomised, double blinded placebo controlled, parallel-group, multi-centre trial on liraglutide's safety, efficacy and action on liver histology and metabolism in overweight patients with non-alcoholic steatohepatitis, with or without type II diabetes
  • PBC Genetics Study- Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis
  • STOPAH- Steroids or pentoxifylline for alcoholic hepatitis 
  • TACE-2- Evaluation of sorafenib in combination with transarterial chemoembolization (TACE) in patients with unresectable HCC
  • UK-PSC- A UK collaborative study to determine the genetic basis of Primary Sclerosing Cholangitis 

Hull and East Yorkshire Hospitals NHS Trust

  • Diligen- Pharmocogenetics of drug induced liver injury.
  • LEAN- A 48-week phase II, randomised, double blinded placebo controlled, parallel-group, multi-centre trial on liraglutide's safety, efficacy and action on liver histology and metabolism in overweight patients with non-alcoholic steatohepatitis, with or without type II diabetes
  • HCV Research UK- Host and Viral factors associated with outcomes of infection with hepatitis C virus  
  • PBC Genetics Study- Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis  
  • STOPAH- Steroids or pentoxifylline for alcoholic hepatitis 
  • TACE-2- Evaluation of sorafenib in combination with transarterial chemoembolization (TACE) in patients with unresectable HCC
  • UK-PSC- A UK collaborative study to determine the genetic basis of Primary Sclerosing Cholangitis

Rotherham NHS Foundation Trust

  • Diligen- Pharmocogenetics of drug induced liver injury
  • PBC Genetics Study- Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis

 Sheffield Hospitals NHS Foundation Trust

  • Diligen- Pharmocogenetics of drug induced liver injury
  • GenomALC - Genetic risk factors for alcoholic cirrhosis, genome-wide case control study
  • HCV Research UK- Host and Viral factors associated with outcomes of infection with hepatitis C virus  
  • PBC Genetics Study- Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis  
  • STOPAH- Steroids or pentoxifylline for alcoholic hepatitis 
  • UK-PSC- A UK collaborative study to determine the genetic basis of Primary Sclerosing Cholangitis

 

 Sites also take part in a number of industry led studies.